back Chininum Arsenicosum

Synonym.- Arseniate of Quinine.

Preparation.- Triturations.


This drug has not been extensively proved, our knowledge of its action being chiefly derived from clinical sources.  It seems to affect the blood composition, the mucous tissues and the nervous system, giving rise to arthritic conditions, low inflammatory states, especially involving the mucous membranes, and accompanied by great exhaustion of the vital forces.  It thus becomes homoeopathic to diphtheria and malignant scarlatina, in both of which affections it has been repeatedly and successfully used.  It also produces a fever closely simulating an intermittent, while the neuralgias resulting from its use are periodical in their character.  It has been successfully used in various malarial affections. Its action evidently combines, more or less, the effects of both Arsenic and Quinine, from each of which, however, it is markedly different in the totality of its symptoms.


Mind.- oDepressed spirits; mental dullness; wishes to be quiet and let alone (Gels.).  oAnxiety and nightly delirium.  oIrritable mood precedes the headache.

Head.- oHemicrania, worse from bodily or mental exercise; also in consequence of fright. Confused feeling in head. Severe, darting, tortuous pains running up into the head and preventing sleep.  Frontal and occipital headache. oNeuralgic pain in right temple and above eye.  oTearing, boring pain in left side of head, affecting the eye, with flickering, pain and lachrymation; ringing in ears, nausea and vomiting during the attack, which regularly appears at midnight (Chin. sulph.).

Eyes. - oIntense photophobia and spasms of orbicularis muscles, gushing hot tears, large ulcers attacking each eye; aggravation from midnight until 3 a.m.; keratitis.  Scrofulous ophthalmia ; worse after midnight.  oFlickering before left eye, with pain and lachrymation; in hemicrania.

Ears. - oRinging in ears; hemicrania (Chin, sulph.).

Nose.- Fluent coryza, profuse discharge.  oNose stopped up with a purulent and bloody substance; diphtheria.  oCorners of nose excoriated; diphtheria (Arum).

Face. - oPale, sallow and bloated; in intermittent fever (Ars., Natr. mur.).  oSwelling of the submaxillary and parotid glands; in diphtheria.  oBlueness of the lips; in tuberculosis.

Mouth.- oTongue coated thick and brown; diphtheria.  oFoetororis ; in diphtheria and scarlatina.

Throat. - oMalignant angina during scarlatina, with paleness of skin, quick exhaustion and rapid destruction of mucous membranes of fauces.  oDiphtheria; great fetor oris; submaxillary glands swollen and painful; nose completely stopped up with a purulent bloody substance;  corners of nose excoriated; tongue coated thick and brown; both tonsils covered with a gray exudation, which on disappearing leaves a bloody ulcer with uneven edges; lower half of uvula gangrenous, upper half covered with exudation; posterior wall of fauces completely covered with exudation; swallowing of liquids very difficult; great prostration; sleeplessness ; pulse small, very frequent.

Stomach.- oThirst which cannot be appeased, during attacks of suffocation; in tuberculosis.  oEggs and fish cause painless diarrhoea at once.  oNausea and vomiting, followed by sleep (Ant. tart.), hemicrania.

Abdomen. - oLeft hypochondriac region enlarged; also abdomen bloated; in intermittent fever.

Stool. - oDiarrhoea from malaria (Chin. sulph.); stools thin, watery,. offensive (Ars.); with pains in bowels.

Urinary Organs. - oSpasmodic retention of urine.

Respiratory Organs.- oHoarseness in diphtheria; seemed to prevent diphtheritic membrane from spreading to larynx.  oAttacks of suffocation begin in morning and last till noon, with blue lips, hands and nails.  Tuberculosis.  oMust sit bent forward, and, if possible, at an open window during attack of suffocation (Ars., Carb. v.,); worse in any other position.  oDyspnoea with anxiety; in tuberculosis. oSenile sub-acute catarrh with periodical fever, generally worse at night.  oParalysis of respiratory muscles on left side; intercostal neuralgia.

Heart and Pulse. - oAngina pectoris, with dropsical symptoms, venous hypermmia and cyanosis. Trembling of heart ; palpitation, noticed on leaning against back.  Sensation as if heart had stopped; beats not perceptible; action irregular.  Pulse small; very frequent (200); irregular.  oViolent neuralgic pain in left mammary region, as though torn with red hot tongs; intercostal neuralgia.

Limbs.- oBlueness of hands and nails : tuberculosis. oLimbs icy-cold; tuberculosis.

Generalities.- oGreat prostration.  Epileptiform spasms.

Sleep.- oDeep sleep after suffocative attacks.  oRestless sleep ; sleeplessness.

Fever.- intermittent fever; chill always in forenoon, not at a regular hour; sometimes once every day, again every other day; sometimes paroxysms close with perspiration, sometimes without; before attack, headache, yawning and stretching.  Chilliness coming in - intermittent fever; chill always in forenoon, not at a regular hour; sometimes once every day, again every other day; sometimes paroxysms close with perspiration, sometimes without; before attack, headache, yawning and stretching.  Chilliness coming in waves in evening, with restlessness; gooseflesh; worse on moving hands and feet to a cool place in bed, also on motion, and by thinking of it.  After chill, fever toward midnight; pulse full and strong, with inclination to throw off covers. No sweat after fever, but weak broken-up feeling in morning and no appetite for breakfast.  od">Conditions.- Hydrogenoid constitution (Aran.).

Compare.- Apis, Are., Aran., Chin, sulph., Cinch.


THERAPEUTICS. The clinical range of this drug has already been sufficiently set forth and need not be repeated. Its chief use is in the treat- ment of intermittent fever and other diseases due to malarial poisoning, and in malignant forms of diphtheria and scarlet fever.

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